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  • AIDS panel reiterates call for prison needle exchange

    By Carol Sanders, Winnipeg Free Press
    February 3, 2010
    Source: Montreal Gazette
    WINNIPEG — The longer Parliament is on hold, the longer prison inmates are sharing dirty needles and diseases with the community at large, former prisoners and health advocates say.
    The Canadian HIV/AIDS Legal Network was supposed to appear Tuesday before the Commons Standing Committee on Public Safety [...]

  • Vaccine stops TB in African HIV trial

    Last Updated: Friday, January 29, 2010
    Source: CBC News
    An experimental vaccine helps prevent tuberculosis in people infected with HIV, researchers have found.
    The Mycobacterium vaccae, or MV vaccine, reduced the rate of tuberculosis by 39 per cent among 2,000 people infected with HIV in Tanzania, researchers said in Friday’s online issue of the journal AIDS.
    Tuberculosis accounts for [...]

  • Armed conflicts have an impact on the spread of tuberculosis: the case of the Somali Regional State of Ethiopia

    Author: Abdi GeleGunnar Bjune
    Credits/Source: Conflict and Health 2010, 4:1
    Source: 7th Space Interactive
    A pessimistic view of the impact of armed conflicts on the control of infectious diseases has generated great interest in the role of conflicts on the global TB epidemic. Nowhere in the world is such interest more palpable than in the Horn of Africa [...]

  • Yukon fights TB spread with control team

    Tuesday, January 26, 2010 | 5:17 PM CT
    Source: CBC News
    Health officials in the Yukon are working to stop the spread of tuberculosis in the territory, which has one of the highest infection rates in Canada.
    Chief medical officer Dr. Brendan Hanley said the Yukon currently has 26 active cases of TB in three undisclosed rural communities.
    Two [...]

  • China's TB control project avoids 770,000 deaths

    Source: Xinhua
    BEIJING, Jan. 20 (Xinhua) — A total of 770,000 deaths from tuberculosis (TB) were avoided over the past eight years in China thanks to a large-scale TB control project, it was announced Wednesday.
    The project covering 670 million Chinese, nearly half of China’s population, also prevented 20 million people from getting infected with TB bacteria.
    China’s [...]

  • Glaxo offers free access to potential malaria cures

    Exclusive: GSK boss says drug companies must balance need to satisfy shareholders with social responsibility
    Sarah Boseley, health editor
    Wednesday 20 January 2010
    Source: The Guardian
    The chief executive of the world’s second biggest pharmaceutical company will today announce that he is putting into the public domain thousands of potential drugs that might cure malaria.
    Andrew Witty, the British boss [...]

  • Circumcising babies could help Africa AIDS fight

    Tue Jan 19, 2010 6:04pm GMT
    By Kate Kelland
    Source: Reuters
    LONDON (Reuters) - Circumcising newborn boys to stop them becoming infected with the AIDS virus in later life is more cost-effective than circumcising adult men, Rwandan health experts said on Tuesday.
    A study by Agnes Binagwaho and colleagues at Rwanda’s health ministry found that the operation, which has [...]

  • For doctors in Haiti, worst is yet to come

    Source: Reuters
    Maggie Fox, Health and Science Editor
    WASHINGTON
    Mon Jan 18, 2010 12:01pm EST
    WASHINGTON (Reuters) - An earthquake killing up to 200,000 people would have been bad enough anywhere, but in Haiti, where AIDS, tuberculosis and malaria are rampant, children are malnourished and hygiene is already a challenge, it may create one of the worst medical disasters [...]

  • China strives to make medical prescriptions affordable to all

    2010-01-15 15:15:00
    by Xinhua writers Bai Xu, Yang Dingdu, Shen Chong
    Source: Xinhua News
    WUHAN, Jan. 15 (Xinhua) - Wang Zhengyan became a celebrity recently after a “best doctors” poll from local people. She has been a doctor for 26 years.
    “She is loved by patients because she always prescribes medicines [...]

  • Atlantic Examines Drug-Resistant TB Control Worldwide

    Thursday, January 14, 2010
    Source: Kaiser Global Health Policy Report
    The Atlantic examines the emergence of drug-resistant strains of tuberculosis around the world, with a look at the situation in South Africa. “[T]he resurgence of tuberculosis is not limited to South Africa. India and China have the largest numbers of tuberculosis cases, and multi-drug-resistant tuberculosis (MDR-TB) has [...]

  • New Study Raises Concerns About HIV-Drug Resistance

    By Eben Harrell
    Thursday, Jan. 14, 2010
    Source: Time
    Last January a team of scientists at the World Health Organization (WHO) published a study in the British medical journal the Lancet making the audacious claim that the tools already exist to end the AIDS epidemic. Doctors have long noted that antiretrovirals — the drugs commonly used to [...]

  • Clean-Cut: Study Finds Circumcision Helps Prevent HIV and Other Infections

    The first microbiome study of the penis offers some clues as to why removing foreskin cuts the risk of HIV infection in circumcised men
    By Carina Storrs
    Source: Scientific American
    The World Health Organization declared three years ago that circumcision should be part of any strategy to prevent HIV infection in men. The organization based its recommendation on [...]

  • Tobacco use prevalence, knowledge, and attitudes among newly diagnosed tuberculosis patients in Penang State and Wilayah Persekutuan Kuala Lumpur, Malaysia

    Author: Ahmed Awaisu Mohamad, Haniki Nik Mohamed Noorizan, et al.
    Credits/Source: Tobacco Induced Diseases 2010, 8:3
    Source: 7th Space Interactive
    There is sufficient evidence to conclude that tobacco smoking is strongly linked to tuberculosis (TB) and a large proportion of TB patients may be active smokers. In addition, a previous analysis has suggested that a considerable proportion [...]

  • Circumcision health benefit virtually nil, study finds

    Little evidence that world’s most common surgical procedure can prevent sexually transmitted infections, urinary tract infections and penile cance
    André Picard
    Tuesday, Jan. 12, 2010
    Source: The Globe and Mail
    While it is the most common surgical procedure in the world, there is virtually no demonstrable health benefit derived from circumcision of either newborns or adults, a new study [...]

  • Study finds that UNICEF program in Africa fails to save more children

    By Maria Cheng (CP) – Jan 11, 2010
    Source: The Canadian Press
    LONDON — A UNICEF program that spent $27 million to decrease child deaths from disease in West Africa has failed, according to a new study that found a higher survival rate in some regions that weren’t included in the program.
    The U.N. children’s agency pursued strategies [...]


New malaria drugs ‘too expensive’ for most Ugandans

Source: guardian.co.uk, Tuesday November 11 2008 09.43 GMT

Effective malaria drugs are too expensive in Uganda and often unavailable, forcing families to fall back on drugs that are cheap, but no longer work well, a new report reveals.

Even within Africa, Uganda is particularly hard hit by malaria, which is responsible for 20 to 23% of all deaths. Small children and pregnant women are worst affected.

Treating malaria has become more difficult because the parasite causing the disease, which is carried in Africa by the anopheles mosquito, has become resistant to one drug after another. But new drug compounds derived from a Chinese plant, known as the artemisinins, offer renewed hope and have become the centrepiece of a major UN-led strategy to defeat, and even eradicate, the disease.

A child in Katine receiving treatment for malaria A new report from the Medicines for Malaria Venture, together with Uganda’s ministry of health, the World Health Organisation (WHO) and the health consumer organisation HEPS-Uganda, reveals, however, that artemisinin combination therapies (ACTs), now supposed to be first-line treatment throughout Africa, are not getting to the people who need them.

Nine districts of Uganda, including Soroti, the nearest town to the sub-county of Katine in north east Uganda, were studied to establish what malaria drugs people were able to obtain, either in public health centres and hospitals or in private pharmacies. The researchers found that the artemisinin compounds were often not available in public health centres. Only around 60% of public health facilities in Soroti had any pack-size of the first-line recommended treatment, called artemether-lumefantrine. NGO and mission facilities had slightly more. Stocks tended to be low or very low everywhere, suggesting that “stock-outs” - a common occurrence across Uganda, in which the dispensary runs out completely - were imminent.

And although private pharmacies and drug stores are far better supplied with all medicines than the public sector (where drugs are free), they had few artemisinin treatments. The private drug shops sell what the customer will buy. Families who have a sick child will buy the very cheap drugs they have used for many years - quinine, chloroquine and sulfadoxine-pyrimethamine (SP) - which drug stores will sell them one tablet at a time. The cheapest of these old and increasingly ineffectual drugs cost 12 US cents. Artemisinin combinations, on the other hand, cost between $5.40 and $12.

That puts the recommended ACT way beyond most budgets. “All anti-malarials, let alone the expensive ACTs, are unaffordable to the average household, which has little or no disposable income left after purchase of food and other essential equipment,” says the report.

“An average household is assumed to have two adults, three children (aged 15, seven and two years) and an annual income of 600,000 Ugandan shillings ($3,600). More than 40% of households live on less than this amount.”

It would cost a family the equivalent of 90 months of primary schooling to pay the bill for a year’s supply of artemether-lumefantrine from a private drug store (even if they could find it) - or 62 days worth of food for the household.

Yet it is important that Ugandan families get the ACTs that the WHO now recommends and the Ugandan government endorses. The authors of the report say that across Africa, ACTs must be made available in private pharmacies and drug stores and that the price has to come down.

“Governments and donors will not win the fight against malaria and poverty unless they continue to strengthen the public health system. However, the study leaves us in no doubt that ACTs must also be made available in the private sector at a price that people can afford,” said Prof Awa Marie Coll-Seck, executive director of the Roll Back Malaria Partnership. “It presents evidence on the urgent need for action to ensure ACTs reach more people, quickly. There is no time to waste.”

Uganda’s minister of health, Dr Stephen Mallinga, said it had been proud to participate in a piece of groundbreaking work. “Three hundred and fifty Ugandan children die every day due to malaria in my country,” he said. “This report provides clear evidence on how we can make life-saving ACTs available to this vulnerable population.”

View article at <a href=”http://www.guardian.co.uk/katine/2008/nov/11/uganda-malaria” target=”_blank”>guardian.co.uk</a>

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McGill Global AIDS Coalition is an HIV/AIDS advocacy group dedicated to the eradication of HIV/AIDS and to the realization, worldwide, of the right to health. We are committed to helping to create an effective student advocacy network in Canada and to educating the McGill and Montreal community on global health issues
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